Future trends in nanobiosensor technology

The sensor consists of carbon nanotubes, and it can also be developed to detect other molecules such as glucose. Professor Starino is developing new sensors for diabetics. If successful, patients will no longer need to test blood samples.

With the development of cross-fusion of nanotechnology and biosensors, more and more new nanobiosensors have emerged, such as quantum dots, DNA, oligonucleoside ligands and other nanobiosensors.

Nano sensor implanted for up to 1 year

Recently, the Massachusetts Institute of Technology's Starino Laboratory has developed a sensor that can be implanted subcutaneously in the human body and can detect nitric oxide content in the human body within one year. This time has set a new record of the implantation time of nano-sensors in human body.

It is reported that the sensor is composed of carbon nanotubes, and a sensor for detecting other molecules such as glucose can also be developed. Professor Starino is developing new sensors for diabetics. If successful, patients will no longer need to test blood samples.

Nitric oxide is one of the most important messenger molecules in human cells, its main role is to transmit information in the brain and other immune system functions. In many cancer cells, the amount of nitric oxide is quite unstable, but the medical community still does not understand the difference between the expression of nitric oxide in healthy and cancer cells.

Future development direction of nanobiosensors

According to Zhao Yongsheng, a key laboratory of the Institute of Chemistry, Chinese Academy of Sciences, the future development direction of nano-biosensors should be integrated multifunctional, portable, and disposable rapid detection and analysis machines, which can be widely used in food, environment, battlefield, Rapid detection of human diseases and other fields.

For example, rapid and sensitive detection of pathogens or pesticide residues in food and beverages; remote detection and control of polluted gases or polluted metal ions in the environment; rapid real-time detection of human blood components and pathogens, and rapid detection of battlefield biochemical weapons and explosives .

However, the new generation of nanobiosensors also face many challenges, such as higher sensitivity, specificity, biocompatibility, integration of multiple technologies, simplified detection methods, preparation processes, mass production, and cost-effectiveness.

In this regard, Zhao Yongsheng said that the molecular self-assembly process is simple and controllable, can be quickly replicated, and has a low cost. It has an important role in promoting the development of biosensors and is conducive to high-sensitivity, low-cost, disposable nano-biology The development of sensors. The biomolecule self-assembly technology is more worthy of attention. It has natural biocompatibility and excellent binding performance, or it will become another new field of biosensor development.

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